{"id":68,"date":"2016-01-29T12:48:12","date_gmt":"2016-01-29T12:48:12","guid":{"rendered":"http:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/?p=68"},"modified":"2018-06-14T15:49:56","modified_gmt":"2018-06-14T14:49:56","slug":"chemengcatchup-episode-3-professor-aline-miller","status":"publish","type":"post","link":"https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/2016\/01\/29\/chemengcatchup-episode-3-professor-aline-miller\/","title":{"rendered":"#ChemEngCatchUp Episode 3 &#8211; Professor Aline Miller"},"content":{"rendered":"<figure id=\"attachment_72\" aria-labelledby=\"figcaption_attachment_72\" class=\"wp-caption alignleft\" ><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-72\" src=\"https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/wp-content\/uploads\/sites\/51\/2016\/01\/Empire-State-Blog.jpg\" alt=\"Aline and her children at the Empire State Building\" width=\"435\" height=\"323\" srcset=\"https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/wp-content\/uploads\/sites\/51\/2016\/01\/Empire-State-Blog.jpg 435w, https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/wp-content\/uploads\/sites\/51\/2016\/01\/Empire-State-Blog-300x223.jpg 300w\" sizes=\"auto, (max-width: 435px) 100vw, 435px\" \/><figcaption id=\"figcaption_attachment_72\" class=\"wp-caption-text\">Aline and her children at the Empire State Building<\/figcaption><\/figure>\n<p>Hello all! Thanks for coming back for the latest\u00a0<a href=\"https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog?s=%23ChemENGCATCHUP\">#ChemEngCatchUp<\/a>.\u00a0Can you believe we&#8217;re on\u00a0Episode 3 already.<\/p>\n<p>From the viewing figures it seems that Episode 1\u00a0<a href=\"https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/2015\/11\/27\/chemengcatchup-episode-1-dr-james-winterburn\/\">James Winterburn<\/a>\u00a0and Episode 2 with <a href=\"https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/2015\/12\/18\/chemengcatchup-episode-2-dr-thomas-vetter\/\" target=\"_blank\">Thomas Vetter<\/a>\u00a0went down very well, but I&#8217;d love to know your thoughts on them. Or on any part of the blog. Please fell free to use the comment section below!<\/p>\n<p>Today we meet <a href=\"http:\/\/www.ceas.manchester.ac.uk\/people\/staff\/profile\/?ea=Aline.Miller&amp;pg=1\" target=\"_blank\">Aline Miller<\/a>, a Professor in Biomolecular Engineering with the <a href=\"http:\/\/www.ceas.manchester.ac.uk\/\" target=\"_blank\">School<\/a>. Unsure what Biomolecular Engineering is? I know I was. Not anymore, though, following this fascinating interview with Aline:<\/p>\n<h3><strong>Hi Aline \u2013 thanks for chatting to us. Could you please describe your research for the layman in ten sentences or less?<\/strong><\/h3>\n<div class=\"video-container\"><span class=\"embed-youtube\" style=\"text-align:center; display: block;\"><iframe loading=\"lazy\" class=\"youtube-player\" width=\"640\" height=\"360\" src=\"https:\/\/www.youtube.com\/embed\/QCYhjLouEcY?version=3&#038;rel=1&#038;showsearch=0&#038;showinfo=1&#038;iv_load_policy=1&#038;fs=1&#038;hl=en-GB&#038;autohide=2&#038;wmode=transparent\" allowfullscreen=\"true\" style=\"border:0;\" sandbox=\"allow-scripts allow-same-origin allow-popups allow-presentation allow-popups-to-escape-sandbox\"><\/iframe><\/span><\/div>\n<p>So what we tend to do is we take inspiration from nature. Nature has had many millennia to produce highly organised, highly functional materials with 100% efficiency.<\/p>\n<p>So we take our inspiration from natural materials, from shells, from how bananas organise when they grow, for example. And then we will actually design molecules, and look at how molecules interact with each other, and design them so that they pack and structure in a highly efficient and well organised way.<\/p>\n<p>And then we can use those molecules to make materials on the micro, the miso, and the macroscopic length scale. Then we use those highly ordered, highly controlled materials for everyday applications. Examples include regenerative medicine &#8211; or in understanding how shampoos and conditioners are made so that we can make them more efficiently for the companies that we work with.<\/p>\n<h3><strong>And how can your research benefit the public?<\/strong><\/h3>\n<p>Our research is very much focused on translation. We have developed a spin out company which is looking at developing some of our materials for the regenerative medicine field. So, for example, we\u2019re using some of our peptide hydrogel materials, which we can control the structure and mechanical properties of, for other research groups in other universities to embed cells in, in three dimensions, and then they can grow and proliferate into different types of tissue, from cartilage to bone.<\/p>\n<p>Then we also work with several companies where we translate our structure\/property correlations into processing knowledge to improve the processing of, for example, shampoos and conditioners for <a href=\"http:\/\/www.unilever.co.uk\/\" target=\"_blank\">Unilever<\/a>.<\/p>\n<p>But we also look at pharmaceutical applications and drug delivery devices so we can actually take our material and then target the active therapeutic at a specific site. For example, oncology is one application area. So instead of flooding your body with cancer drugs that end up damaging the healthy and the cancerous tissues, we\u2019re looking at developing our materials so they just deliver the cancer therapeutic to the cancer tissue and not affect the healthy tissue.<\/p>\n<h3><strong>Can you tell us how you first got interested in your research area?<\/strong><\/h3>\n<figure id=\"attachment_73\" aria-labelledby=\"figcaption_attachment_73\" class=\"wp-caption alignright\" ><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-73\" src=\"https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/wp-content\/uploads\/sites\/51\/2016\/01\/Wilmslow-half-blog.jpg\" alt=\"Aline running the Wilmslow half\" width=\"375\" height=\"375\" srcset=\"https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/wp-content\/uploads\/sites\/51\/2016\/01\/Wilmslow-half-blog.jpg 375w, https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/wp-content\/uploads\/sites\/51\/2016\/01\/Wilmslow-half-blog-150x150.jpg 150w, https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/wp-content\/uploads\/sites\/51\/2016\/01\/Wilmslow-half-blog-300x300.jpg 300w\" sizes=\"auto, (max-width: 375px) 100vw, 375px\" \/><figcaption id=\"figcaption_attachment_73\" class=\"wp-caption-text\">Aline running the Wilmslow half<\/figcaption><\/figure>\n<p>I think I first got interested in science because my parents bought me a chemistry set. I used to play around and create explosions and fires and things in the greenhouse when I was younger.<\/p>\n<p>But I spent a year of my undergraduate degree over in the States and that\u2019s when I started getting interested in research. Polymers was an area I was particularly interested in because it seemed at the time to be a thriving industrial community in the States and also the UK- one that had real applications.<\/p>\n<p>So that\u2019s where I started to get interested, and then I actually applied some of the physics that I learnt about polymers to chemical and biological problems. And then we\u2019ve slowly, over the twelve years I\u2019ve been in Manchester, actually taken that fundamental knowledge and turned it into actual products, improving everyday lives of people, really.<\/p>\n<h3><strong>Going back a bit further, then, can you tell us who or what inspired your interests in science and engineering?<\/strong><\/h3>\n<div class=\"video-container\"><span class=\"embed-youtube\" style=\"text-align:center; display: block;\"><iframe loading=\"lazy\" class=\"youtube-player\" width=\"640\" height=\"360\" src=\"https:\/\/www.youtube.com\/embed\/A84V8YZJ7HQ?version=3&#038;rel=1&#038;showsearch=0&#038;showinfo=1&#038;iv_load_policy=1&#038;fs=1&#038;hl=en-GB&#038;autohide=2&#038;wmode=transparent\" allowfullscreen=\"true\" style=\"border:0;\" sandbox=\"allow-scripts allow-same-origin allow-popups allow-presentation allow-popups-to-escape-sandbox\"><\/iframe><\/span><\/div>\n<figure id=\"attachment_74\" aria-labelledby=\"figcaption_attachment_74\" class=\"wp-caption alignleft\" ><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-74\" src=\"https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/wp-content\/uploads\/sites\/51\/2016\/01\/Remembrance-Day-blog.jpg\" alt=\"Aline and her children getting ready for Beaver Scouts!\" width=\"375\" height=\"375\" srcset=\"https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/wp-content\/uploads\/sites\/51\/2016\/01\/Remembrance-Day-blog.jpg 375w, https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/wp-content\/uploads\/sites\/51\/2016\/01\/Remembrance-Day-blog-150x150.jpg 150w, https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/wp-content\/uploads\/sites\/51\/2016\/01\/Remembrance-Day-blog-300x300.jpg 300w\" sizes=\"auto, (max-width: 375px) 100vw, 375px\" \/><figcaption id=\"figcaption_attachment_74\" class=\"wp-caption-text\">Aline and her children getting ready for Beaver Scouts!<\/figcaption><\/figure>\n<p>I think I was always interested in maths; I was always interested in problem solving. In a very logical black and white way, if you like. And I worked with a few people in my undergraduate who really encouraged me to ask questions about unknown topics. That\u2019s when I started to get interested in research. And in trying to understand and come to some conclusion and develop rules for how molecules self-assemble and affect material properties.<\/p>\n<p>My post-doc supervisor is someone who inspired me to do research. She\u2019s eminent in her field and a very good role model for someone who wants to combine a career and family life.<\/p>\n<h3><strong>On that note, then \u2013 what do you get up to in your spare time?<\/strong><\/h3>\n<p>Well I have a family; I have three young boys aged six, eight, and ten. So they take up most of my time! But I also run beaver scouts which my boys have gone through and my youngest is now in and it\u2019s a lot of fun, something very different from work. But again, you have to just be organised and plan and coordinate activities for them.<\/p>\n<p>I also do a lot of running. I like long distance running and it\u2019s a good stress relief from the daily grind!<\/p>\n<h3><strong>I\u2019d definitely agree with that! One more question, then \u2013 can you tell us how being here in Manchester has helped your work and research?<\/strong><\/h3>\n<div class=\"video-container\"><span class=\"embed-youtube\" style=\"text-align:center; display: block;\"><iframe loading=\"lazy\" class=\"youtube-player\" width=\"640\" height=\"360\" src=\"https:\/\/www.youtube.com\/embed\/wjCXKVPQLBY?version=3&#038;rel=1&#038;showsearch=0&#038;showinfo=1&#038;iv_load_policy=1&#038;fs=1&#038;hl=en-GB&#038;autohide=2&#038;wmode=transparent\" allowfullscreen=\"true\" style=\"border:0;\" sandbox=\"allow-scripts allow-same-origin allow-popups allow-presentation allow-popups-to-escape-sandbox\"><\/iframe><\/span><\/div>\n<p>I think working in a <a href=\"http:\/\/www.ceas.manchester.ac.uk\/\" target=\"_blank\">chemical engineering<\/a> department, as a chemist who has worked in chemistry and physics departments, has influenced my work because we\u2019ve focused a lot of the end product and actually translating our fundamental science into engineered products.<\/p>\n<p>But also <a href=\"http:\/\/www.manchester.ac.uk\/\" target=\"_blank\">Manchester<\/a>, it\u2019s a very big university, and that had got its benefits because we work with experts in <a href=\"http:\/\/www.chemistry.manchester.ac.uk\/\" target=\"_blank\">chemistry<\/a>, in <a href=\"http:\/\/www.pharmacy.manchester.ac.uk\/\" target=\"_blank\">pharmacy<\/a>, and in the <a href=\"http:\/\/www.mhs.manchester.ac.uk\/\" target=\"_blank\">medicine faculty<\/a>.<\/p>\n<p>So we\u2019re actually really taking our materials from the lab, and the creation of our materials that we do here, all the way through to clinical applications. And that\u2019s a huge benefit that Manchester\u2019s enabled us to realise.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Brilliant, thanks Aline. What an interesting interview. After only 3 episodes, I think we&#8217;re already seeing an amazing variation of research taking place in the School. It&#8217;s great to hear that the work our researchers are doing can help with things as varied as regenerative medicine and haircare! Who knew?<\/strong><\/p>\n<p><strong>And just to continue the theme of variety, the series will be back in a month&#8217;s time when we talk to Soil Scientist Nima Shokri! See you then.\u00a0<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>So we take our inspiration from natural materials, from shells, from how bananas organise when they grow, for example. And then we will actually design molecules, and look at how molecules interact with each other, and design them so that they pack and structure in a highly efficient and well organised way.<\/p>\n","protected":false},"author":90,"featured_media":71,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[82],"tags":[28,30,29],"class_list":{"0":"post-68","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-meet-the-department","8":"tag-biomolecular-engineering","9":"tag-oncology","10":"tag-regenerative-medicine","11":"entry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>#ChemEngCatchUp Episode 3 - Professor Aline Miller - Department of Chemical Engineering Blog<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.mub.eps.manchester.ac.uk\/ceasblog\/2016\/01\/29\/chemengcatchup-episode-3-professor-aline-miller\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"#ChemEngCatchUp Episode 3 - Professor Aline Miller - Department of Chemical Engineering Blog\" \/>\n<meta property=\"og:description\" content=\"So we take our inspiration from natural materials, from shells, from how bananas organise when they grow, for example. 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